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CoraLite®594-conjugated PGRMC2 Monoclonal antibody

PGRMC2 Monoclonal Antibody for IF

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse

Applications

IF

Conjugate

CoraLite®594 Fluorescent Dye

CloneNo.

5F10D7

Cat no : CL594-60249

Synonyms

DG6, PGRMC2, PMBP



Tested Applications

Positive IF detected inhuman cervical cancer tissue
For other applications, we recommend the unconjugated version of this antibody, 60249-1-Ig

Recommended dilution

ApplicationDilution
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of CL594-60249 is PGRMC2 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PGRMC2 fusion protein Ag20077 相同性解析による交差性が予測される生物種
Full Name progesterone receptor membrane component 2
Calculated molecular weight 223 aa, 24 kDa
Observed molecular weight 24+28 kDa
GenBank accession numberBC016692
Gene symbol PGRMC2
Gene ID (NCBI) 10424
RRIDAB_2919905
Conjugate CoraLite®594 Fluorescent Dye
Excitation/Emission maxima wavelengths588 nm / 604 nm
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

Membrane-associated progesterone receptor component 2 (PGRMC2), also known as DG6 or PMBP, belongs to the cytochrome b5 family. This protein might play a role in cancer. The gene of PGRMC2 maps to chromosome 4q26, and encodes a 223-amino acid single-pass membrane protein with a cytochrome b5 heme-binding domain in its cytoplasmic domain. PGRMC2 has a calculated molecular weight of 24 kDa. The band of about 28 kDa detected by this monoclonal antibody is unknown but may represent phosphorylated form of PGRMC2 (PMID: 28104494).

Protocols

Product Specific Protocols
IF protocol for CL594 PGRMC2 antibody CL594-60249Download protocol
Standard Protocols
Click here to view our Standard Protocols