CoraLite®594-conjugated MTAP Monoclonal antibody
MTAP Monoclonal Antibody for IF
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat
Applications
IF
Conjugate
CoraLite®594 Fluorescent Dye
CloneNo.
2B1G6
Cat no : CL594-66706
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive IF detected in | HeLa cells |
For other applications, we recommend the unconjugated version of this antibody, 66706-1-Ig
Recommended dilution
| Application | Dilution |
|---|---|
| Immunofluorescence (IF) | IF : 1:50-1:500 |
| Sample-dependent, check data in validation data gallery | |
Product Information
CL594-66706 targets MTAP in IF applications and shows reactivity with Human, Mouse, Rat samples.
| Tested Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | MTAP fusion protein Ag17954 相同性解析による交差性が予測される生物種 |
| Full Name | methylthioadenosine phosphorylase |
| Calculated molecular weight | 283 aa, 31 kDa |
| Observed molecular weight | 31 kDa |
| GenBank accession number | BC018625 |
| Gene symbol | MTAP |
| Gene ID (NCBI) | 4507 |
| RRID | AB_2883617 |
| Conjugate | CoraLite®594 Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 588 nm / 604 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
MTAP is a 5-deoxy-5-methylthioadenosine (MTA) phosphorylase, converting MTA to salvageable intermediates including adenine and 5-methylthioribose-1-phosphate. MTAP is abundant in normal cells, but it is frequently found to be deleted in a variety of cancers. Its deficiency is common in cancer cell lines as well as in primary leukemia, lung cancer, melanoma, bladder cancer, gliomas and breast cancer.
Protocols
| Product Specific Protocols | |
|---|---|
| IF protocol for CL594 MTAP antibody CL594-66706 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
