IL-16 Monoclonal antibody

IL-16 Monoclonal Antibody for WB,ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB,ELISA

Conjugate

Unconjugated

CloneNo.

1C4C7

Cat no : 66145-1-Ig

Synonyms

HsT19289, IL 16, IL16, IL-16, LCF, prIL 16, Pro interleukin 16



Tested Applications

Positive WB detected inRecombinant protein

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 66145-1-Ig is IL-16 Fusion Protein expressed in E. coli.

Tested Reactivity human
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen IL-16 fusion protein Ag16466 相同性解析による交差性が予測される生物種
Full Name interleukin 16 (lymphocyte chemoattractant factor)
Calculated molecular weight 130 aa, 15 kDa
Observed molecular weight 37 kDa
GenBank accession numberBC040272
Gene symbol IL16
Gene ID (NCBI) 3603
RRIDAB_2881542
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. It is mainly produced by T lymphocytes but also by other immune cells, neuronal cells, fibroblasts and epithelial cells. The signaling process of this cytokine is mediated by CD4. IL-16 induces chemotaxis of CD4+ cells such as lymphocytes, eosinophils, and dendritic cells by ligating CD4 directly at a site distinct from other ligands. Among its multiple functions, IL-16 is a T cell chemoattractant involved in T helper cell inflammatory responses and the regulation of both T cell growth, and responsiveness to regulatory cytokines. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control.

Protocols

Product Specific Protocols
WB protocol for IL-16 antibody 66145-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols