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  • Featured Product
  • KD/KO Validated

CoraLite® Plus 488-conjugated DRP1 (C-terminal) Polyclonal antibody

DRP1 (C-terminal) Polyclonal Antibody for FC (Intra)

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

FC (Intra)

Conjugate

CoraLite® Plus 488 Fluorescent Dye

Cat no : CL488-12957

Synonyms

DLP1, DNM1L, Dnm1p/Vps1p like protein, DRP1, DRP1 (C-terminal), DVLP, DYMPLE, dynamin 1 like, Dynamin 1 like protein, Dynamin like protein, Dynamin like protein 4, Dynamin like protein IV, Dynamin related protein 1, DYNIV 11, FLJ41912, HDYNIV, VPS1

Validation Data Gallery

Applications:
  • FC experiment of HeLa using CL488-12957

    FC experiment of HeLa using CL488-12957

    1X10^6 HeLa cells were intracellularly stained with 0.4 ug CoraLite® Plus 488 Anti-Human DRP1 (C-terminal) (CL488-12957) (red), or 0.4 ug Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).

Tested Applications

Positive FC detected inHeLa cells
For other applications, we recommend the unconjugated version of this antibody, 12957-1-AP

Recommended dilution

ApplicationDilution
Flow Cytometry (FC)FC : 0.40 ug per 10^6 cells in a 100 µl suspension
Sample-dependent, check data in validation data gallery

Product Information

CL488-12957 targets DRP1 (C-terminal) in FC (Intra) applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DRP1 (C-terminal) fusion protein Ag3644 相同性解析による交差性が予測される生物種
Full Name dynamin 1-like
Calculated molecular weight 736 aa, 82 kDa
Observed molecular weight 75-80 kDa
GenBank accession numberBC024590
Gene symbol DNM1L
Gene ID (NCBI) 10059
RRIDAB_2919066
Conjugate CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
Storage ConditionsStore at -20°C. Avoid exposure to light. Aliquoting is unnecessary for -20oC storage.

Background Information

DNM1L(Dynamin-1-like protein) , also known as dynamin-related protein 1 (DRP1), belongs to the dynamin family of large GTPases that mediate membrane remodeling during a variety of cellular processes. DNM1L has an important role in the division of growing mitochondria and peroxisomes and also mediates outer mitochondrial membrane fission in mammalian cells. DNM1L is ubiquitously expressed with abundant expression in skeletal muscle, heart, kidney and brain.Variable isoforms of DNM1L have been reported in a tissue-specific manner due to the alternative splicing.

Protocols

Product Specific Protocols
FC protocol for CL Plus 488 DRP1 (C-terminal) antibody CL488-12957Download protocol
Standard Protocols
Click here to view our Standard Protocols