FBXO7 Polyclonal antibody
FBXO7 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, CoIP, ELISA
Conjugate
Unconjugated
Cat no : 10696-1-AP
Synonyms
Validation Data Gallery
Applications:
Tested Applications
| Positive WB detected in | HeLa cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Sample-dependent, check data in validation data gallery | |
Published Applications
| WB | See 1 publications below |
| CoIP | See 1 publications below |
Product Information
10696-1-AP targets FBXO7 in WB, CoIP, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | FBXO7 fusion protein Ag1035 相同性解析による交差性が予測される生物種 |
| Full Name | F-box protein 7 |
| Calculated molecular weight | 59 kDa |
| Observed molecular weight | 59-75 kDa |
| GenBank accession number | BC008361 |
| Gene symbol | FBXO7 |
| Gene ID (NCBI) | 25793 |
| RRID | AB_2246820 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
FBXO7, also named as FBX7, is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO7 recognizes BIRC2 and DLGAP5. It function in phosphorylation-dependent ubiquitination.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for FBXO7 antibody 10696-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Hepatology Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cells. | ||
JCI Insight Chemical inhibition of FBXO7 reduces inflammation and confers neuroprotection by stabilizing the mitochondrial kinase PINK1. |
